Rapid biomimetic total synthesis of (±)-rossinone B.

  title={Rapid biomimetic total synthesis of (±)-rossinone B.},
  author={Ziyang Zhang and Jiahua Chen and Zhen Yang and Yefeng Tang},
  journal={Organic letters},
  volume={12 23},
A biomimetic total synthesis of (±)-rossinone B has been achieved through a highly efficient strategy featuring a series of rationally designed reactions, including a one-pot allylic rearrangement/oxidation reaction to generate the vinyl quinone 27, an intramolecular vinyl quinone Diels-Alder reaction to construct the linear 6-6-5 tricyclic core of 28, and a double conjugate addition/β-elimination cascade to complete the total synthesis of 1.