Rapid apoptosis in the pulmonary vasculature distinguishes non-metastatic from metastatic melanoma cells.

Abstract

The presence of metastases indicates an ominous prognosis in patients with malignancies, yet the factors that distinguish metastatic from non-metastatic tumors remain poorly understood. Here we pursued the hypothesis that apoptosis in vivo would distinguish metastatic cells from non-metastatic cells and developed a novel method for observation of apoptosis… (More)

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