Rapid and inexpensive enzyme inhibition assay of methotrexate.

@article{Yap1986RapidAI,
  title={Rapid and inexpensive enzyme inhibition assay of methotrexate.},
  author={A K Yap and David K Luscombe},
  journal={Journal of pharmacological methods},
  year={1986},
  volume={16 2},
  pages={139-50}
}
A rapid and inexpensive enzyme inhibition procedure has been developed for the assay of methotrexate in biological fluids. The method achieves a high degree of sensitivity, reproducibility, and specificity. No prior separation procedures are required, and there is no cross-reaction with metabolites of methotrexate or other substances such as folinic acid… CONTINUE READING