Rapid and highly specific screening for NPM1 mutations in acute myeloid leukemia

Abstract

NPM1 mutations, the most frequent molecular alterations in acute myeloid leukemia (AML), have become important for risk stratification and treatment decisions for patients with normal karyotype AML. Rapid screening for NPM1 mutations should be available shortly after diagnosis. Several methods for detecting NPM1 mutations have been described, most of which… (More)
DOI: 10.1007/s00277-012-1617-9

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@article{Leibundgut2012RapidAH, title={Rapid and highly specific screening for NPM1 mutations in acute myeloid leukemia}, author={Elisabeth Oppliger Leibundgut and Naomi A. Porret and Marianne Bienz Muggli and Heidi Baumgartner and Meike Dahlhaus and Gabriela M. Baerlocher}, journal={Annals of Hematology}, year={2012}, volume={92}, pages={173-177} }