Rapid and Sensitive Determination of Timosaponin AIII in Rat Plasma by LC-MS/MS and Its Pharmacokinetic Application

@inproceedings{Liu2013RapidAS,
  title={Rapid and Sensitive Determination of Timosaponin AIII in Rat Plasma by LC-MS/MS and Its Pharmacokinetic Application},
  author={Yanping Liu and Yiqiong Pu and Tong Zhang and Yue Ding and Bing Wang and Zhenzhen Cai},
  booktitle={International journal of molecular sciences},
  year={2013}
}
A rapid sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for determination of timosaponin AIII (TA-III) in rat plasma, using ginsenoside Re as an internal standard (IS). TA-III and the IS were detected in MRM mode with a negative ionization electrospray mass spectrometer. The calibration curves were… CONTINUE READING