Rapid and Sensitive Detection of Bartonella bacilliformis in Experimentally Infected Sand Flies by Loop-Mediated Isothermal Amplification (LAMP) of the Pap31 Gene

@inproceedings{Angkasekwinai2014RapidAS,
  title={Rapid and Sensitive Detection of Bartonella bacilliformis in Experimentally Infected Sand Flies by Loop-Mediated Isothermal Amplification (LAMP) of the Pap31 Gene},
  author={Nasikarn Angkasekwinai and Erin H. Atkins and Richard N. Johnson and John Paul Grieco and Wei Mei Ching and Chien Chung Chao},
  booktitle={PLoS neglected tropical diseases},
  year={2014}
}
BACKGROUND Carrion' disease, caused by Bartonella bacilliformis, remains truly neglected due to its focal geographical nature. A wide spectrum of clinical manifestations, including asymptomatic bacteremia, and lack of a sensitive diagnostic test can potentially lead to a spread of the disease into non-endemic regions where competent sand fly vectors may be present. A reliable test capable of detecting B. bacilliformis is urgently needed. Our objective is to develop a loop-mediated isothermal… CONTINUE READING
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