Rapid activation and hepatic recruitment of innate-like regulatory B cells after invariant NKT cell stimulation in mice.

Abstract

BACKGROUND & AIMS Invariant natural killer T (iNKT) cells are present within the liver and have been implicated in the development of many liver diseases. Upon activation by glycolipid ligands (including α-galactosylceramide; αGalCer), hepatic iNKT cells produce numerous cytokines and recruit both pro-inflammatory and regulatory immune cells. However, the… (More)
DOI: 10.1016/j.jhep.2015.06.007

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