Rapid actin monomer–insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1

@article{Brieher2006RapidAM,
  title={Rapid actin monomer–insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1},
  author={William M Brieher and Hao Yuan Kueh and Bryan A. Ballif and Timothy J Mitchison},
  journal={The Journal of Cell Biology},
  year={2006},
  volume={175},
  pages={315 - 324}
}
Actin filaments in cells depolymerize rapidly despite the presence of high concentrations of polymerizable G actin. Cofilin is recognized as a key regulator that promotes actin depolymerization. In this study, we show that although pure cofilin can disassemble Listeria monocytogenes actin comet tails, it cannot efficiently disassemble comet tails in the presence of polymerizable actin. Thymus extracts also rapidly disassemble comet tails, and this reaction is more efficient than pure cofilin… CONTINUE READING
Highly Cited
This paper has 62 citations. REVIEW CITATIONS
Tweets
This paper has been referenced on Twitter 1 time. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 50 citations

62 Citations

0510'09'12'15'18
Citations per Year
Semantic Scholar estimates that this publication has 62 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 38 references