Rapid access to substituted 2-naphthyne intermediates via the benzannulation of halogenated silylalkynes.


Aryne intermediates are versatile and important reactive intermediates for natural product and polymer synthesis. 2-Naphthynes are relatively unexplored because few methods provide precursors to these intermediates, especially for those bearing additional substituents. Here we report a general synthetic strategy to access 2-naphthyne precursors through an… (More)
DOI: 10.1039/c7sc01625e


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