Rapid Reversal of Human Intestinal Ischemia-Reperfusion Induced Damage by Shedding of Injured Enterocytes and Reepithelialisation

  title={Rapid Reversal of Human Intestinal Ischemia-Reperfusion Induced Damage by Shedding of Injured Enterocytes and Reepithelialisation},
  author={Joep Pm Derikx and Robert A. Matthijsen and Adriaan P. de Bru{\"i}ne and Annemarie A J H M van Bijnen and Erik Heineman and Ronald M. van Dam and Cornelis H. C. Dejong and Wim A. Buurman},
  journal={PLoS ONE},
  pages={951 - 953}
BACKGROUND Intestinal ischemia-reperfusion (IR) is a phenomenon related to physiological conditions (e.g. exercise, stress) and to pathophysiological events (e.g. acute mesenteric ischemia, aortic surgery). Although intestinal IR has been studied extensively in animals, results remain inconclusive and data on human intestinal IR are scarce. Therefore, an experimental harmless model for human intestinal IR was developed, enabling us to clarify the sequelae of human intestinal IR for the first… CONTINUE READING


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