Rapid Identification of Bioactive Compounds Reducing the Production of Amyloid β-Peptide (Aβ) from South African Plants Using an Automated HPLC/SPE/HPLC Coupling System

@article{Kwon2011RapidIO,
  title={Rapid Identification of Bioactive Compounds Reducing the Production of Amyloid $\beta$-Peptide (A$\beta$) from South African Plants Using an Automated HPLC/SPE/HPLC Coupling System},
  author={H. Kwon and J. Cha and Jin-Soo Park and Y. Chun and N. Moodley and V. Maharaj and Sung-Hee Youn and Sungkwon Chung and Hyun-Ok Yang},
  journal={Biomolecules \& Therapeutics},
  year={2011},
  volume={19},
  pages={90-96}
}
Abstract of many novel therapeutic agents (John, 2009). However, the classical bioactivity-guided fractionation for the purifi cation and identi fi cation of biologically active compounds from plants extracts can be tedious process with long time frames (Clark-son et al. , 2006; Harvey, 2007). In addition, the bioassay dur-ing the bioactivity-guided fractionation may be obscured by poor solubility of samples or by fl uorescent or colored sub-stances in samples. A further complication can be… Expand
A new two-dimensional chromatographic method for separation of saponins from steamed Panax notoginseng.
CRINUM; AN ENDLESS SOURCE OF BIOACTIVE PRINCIPLES: A REVIEW. PART V. BIOLOGICAL PROFILE
  • 2013

References

SHOWING 1-10 OF 24 REFERENCES
Natural products as a screening resource.
  • A. Harvey
  • Engineering, Medicine
  • Current opinion in chemical biology
  • 2007
Anti-tumor activity of a 3-oxo derivative of oleanolic acid.
Cytotoxic constituents ofPilea mongolica
Aβ Oligomers – a decade of discovery
...
1
2
3
...