Rapid Genotyping of β-tubulin Polymorphisms in Trichuris trichiura and Ascaris lumbricoides

@inproceedings{Rashwan2017RapidGO,
  title={Rapid Genotyping of β-tubulin Polymorphisms in Trichuris trichiura and Ascaris lumbricoides},
  author={Nour Rashwan and Marilyn Scott and Roger K. Prichard},
  booktitle={PLoS neglected tropical diseases},
  year={2017}
}
  • Nour Rashwan, Marilyn Scott, Roger K. Prichard
  • Published in
    PLoS neglected tropical…
    2017
  • Biology, Medicine
  • BACKGROUND The benzimidazole (BZ) anthelmintics, albendazole (ABZ) and mebendazole (MBZ) are the most common drugs used for treatment of soil-transmitted helminths (STHs). Their intensive use increases the possibility that BZ resistance may develop. In veterinary nematodes, BZ resistance is caused by a single nucleotide polymorphism (SNP) in the β-tubulin isotype 1 gene at codon position 200, 167 or 198, and these SNPs have also been correlated with poor response of human Trichuris trichiura to… CONTINUE READING

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