Rapid Communications Striking Augmentation of Hematopoietic Cell Chimerism in Noncytoablated Allogeneic Bone Marrow Recipients by Flt 3 Ligand and Tacrolimus

@inproceedings{Anand2010RapidCS,
  title={Rapid Communications Striking Augmentation of Hematopoietic Cell Chimerism in Noncytoablated Allogeneic Bone Marrow Recipients by Flt 3 Ligand and Tacrolimus},
  author={Anand and lYENGAR and Andrew C. Bonham and A. ANTONYSAMY and Vladimir M. Subbotin and Noriko Murase and A. Suresh Rao and Thomas E. Starzl and Angus W Thomson},
  year={2010}
}
The influence of granulocyte-macrophage colonystimulating factor (GM-CSF) and the recently identified hematopoietic stem-progenitor cell mobilizing factor flt3 ligand (FL) on donor leukocyte microchimerism in noncytodepleted recipients of allogeneic bone marrow (BM) was compared. BI0 mice (H2b ) given 50XI06 allogeneic (BlO.BR [H2k]) BM cells also received either GM-CSF (4 "g/day s.c.), FL (10 "g/day i.p.), or no cytokine, with or without concomitant tacrolimus (formerly FK506j 2 mg/kg) from… CONTINUE READING