Rapid Cellular Turnover in Adipose Tissue

  title={Rapid Cellular Turnover in Adipose Tissue},
  author={Alessandra Rigamonti and Kristen Brennand and Frank W K Lau and Chad A. Cowan},
  booktitle={PloS one},
It was recently shown that cellular turnover occurs within the human adipocyte population. Through three independent experimental approaches--dilution of an inducible histone 2B-green fluorescent protein (H2BGFP), labeling with the cell cycle marker Ki67 and incorporation of BrdU--we characterized the degree of cellular turnover in murine adipose tissue. We observed rapid turnover of the adipocyte population, finding that 4.8% of preadipocytes are replicating at any time and that between 1-5… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 10 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.
47 Citations
38 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 47 extracted citations


Publications referenced by this paper.
Showing 1-10 of 38 references

The role of PECAM-1 in vascular cell biology

  • PJ Newman
  • Ann N Y Acad Sci
  • 1994
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…