Rapid 3D-imaging of phosphocreatine recovery kinetics in the human lower leg muscles with compressed sensing.

@article{Parasoglou2012Rapid3O,
  title={Rapid 3D-imaging of phosphocreatine recovery kinetics in the human lower leg muscles with compressed sensing.},
  author={Prodromos Parasoglou and Li Feng and Ding Xia and Ricardo Otazo and Ravinder R. Regatte},
  journal={Magnetic resonance in medicine},
  year={2012},
  volume={68 6},
  pages={
          1738-46
        }
}
The rate of phosphocreatine (PCr) resynthesis following physical exercise is an accepted index of mitochondrial oxidative metabolism and has been studied extensively with unlocalized (31)P-MRS methods and small surface coils. Imaging experiments using volume coils that measure several muscles simultaneously can provide new insights into the variability of muscle function in healthy and diseased states. However, they are limited by long acquisition times relative to the dynamics of PCr recovery… CONTINUE READING
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