Rapid, nongenomic steroid actions: A new age?

  title={Rapid, nongenomic steroid actions: A new age?},
  author={Bernhard M. W. Schmidt and D{\'e}sir{\'e}e Gerdes and Martin Feuring and Elisabeth Falkenstein and Michael Christ and Martin Wehling},
  journal={Frontiers in neuroendocrinology},
  volume={21 1},
In the traditional theory of steroid action, steroids bind to intracellular receptors and modulate nuclear transcription after translocation of steroid-receptor complexes into the nucleus. Due to similarities of molecular structure, specific receptors for steroids, vitamin D(3) derivatives, and thyroid hormone are considered to represent a superfamily of steroid receptors. While genomic steroid effects characterized by their delayed onset of action and their sensitivity to blockers of… CONTINUE READING
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