Rapamycin increases RSV RNA levels and survival of RSV-infected dendritic cell depending on T cell contact.


The macrolide rapamycin inhibits mTOR (mechanist target of rapamycin) function and has been broadly used to unveil the role of mTOR in immune responses. Inhibition of mTOR on dendritic cells (DC) can influence cellular immune response and the survival of DC. RSV is the most common cause of hospitalization in infants and is a high priority candidate to… (More)
DOI: 10.1016/j.tiv.2016.07.016