Rapamycin biosynthesis: Elucidation of gene product function.

@article{Gregory2006RapamycinBE,
  title={Rapamycin biosynthesis: Elucidation of gene product function.},
  author={Matthew A Gregory and Hui Hong and Rachel E Lill and Sabine Gaisser and Hrvoje Petkovi{\'c} and Lindsey Low and Lesley S Sheehan and Isabelle Carletti and Sarah J. Ready and Michael John Ward and Andrew L Kaja and Alison J Weston and Iain R Challis and Peter Francis Leadlay and Christine J Martin and Barrie Wilkinson and Rose M Sheridan},
  journal={Organic & biomolecular chemistry},
  year={2006},
  volume={4 19},
  pages={3565-8}
}
The function of gene products involved in the biosynthesis of the clinically important polyketide rapamycin were elucidated by biotransformation and gene complementation.