Corpus ID: 26138055

Ranolazine ( Ranexa ) : A First-in-Class Therapy for Stable Angina

  title={Ranolazine ( Ranexa ) : A First-in-Class Therapy for Stable Angina},
  author={Marilena S. Antonopoulos and Julie N. Lee and Albert Chang},
488 P&T® • September 2007 • Vol. 32 No. 9 INTRODUCTION Angina pectoris (chest pain) is a clinical syndrome characterized by discomfort in the chest, jaw, shoulder, back, or arm. It occurs when the myocardial demand for oxygen (MVO2) exceeds the oxygen supply, leading to myocardial ische mia. Typically, angina is the result of coronary artery disease (CAD), also known as ischemic heart disease (IHD) and coronary heart disease (CHD). CHD remains the single leading cause of death in the U.S… Expand
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