Corpus ID: 26138055

Ranolazine ( Ranexa ) : A First-in-Class Therapy for Stable Angina

@inproceedings{Antonopoulos2007RanolazineR,
  title={Ranolazine ( Ranexa ) : A First-in-Class Therapy for Stable Angina},
  author={Marilena S. Antonopoulos and Julie N. Lee and Albert Chang},
  year={2007}
}
488 P&T® • September 2007 • Vol. 32 No. 9 INTRODUCTION Angina pectoris (chest pain) is a clinical syndrome characterized by discomfort in the chest, jaw, shoulder, back, or arm. It occurs when the myocardial demand for oxygen (MVO2) exceeds the oxygen supply, leading to myocardial ische mia. Typically, angina is the result of coronary artery disease (CAD), also known as ischemic heart disease (IHD) and coronary heart disease (CHD). CHD remains the single leading cause of death in the U.S… Expand
1 Citations

Figures and Tables from this paper

References

SHOWING 1-8 OF 8 REFERENCES
Ranolazine for the treatment of chronic angina and potential use in other cardiovascular conditions.
  • 263
  • Highly Influential
The mechanism of ranolazine action to reduce ischemia-induced diastolic dysfunction
  • 80
  • PDF
Antianginal efficacy of ranolazine when added to treatment with amlo d ipine
  • J Am Coll Cardiol
  • 2006
update : A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee