Ranolazine (Ranexa): A First-in-Class Therapy for Stable Angina


488 P&T® • September 2007 • Vol. 32 No. 9 INTRODUCTION Angina pectoris (chest pain) is a clinical syndrome characterized by discomfort in the chest, jaw, shoulder, back, or arm. It occurs when the myocardial demand for oxygen (MVO2) exceeds the oxygen supply, leading to myocardial ische mia. Typically, angina is the result of coronary artery disease (CAD… (More)


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