Rank ordering plate data facilitates data visualization and normalization in high-throughput screening.

@article{Mangat2014RankOP,
  title={Rank ordering plate data facilitates data visualization and normalization in high-throughput screening.},
  author={Chand Singh Mangat and Amrita Bharat and Sebastian S. Gehrke and Eric D Brown},
  journal={Journal of biomolecular screening},
  year={2014},
  volume={19 9},
  pages={1314-20}
}
High-throughput screening (HTS) of chemical and microbial strain collections is an indispensable tool for modern chemical and systems biology; however, HTS data sets have inherent systematic and random error, which may lead to false-positive or false-negative results. Several methods of normalization of data exist; nevertheless, due to the limitations of each, no single method has been universally adopted. Here, we present a method of data visualization and normalization that is effective… CONTINUE READING