Randomized trial using ultrasound to assess intramuscular vaccination at a 60° or 90° needle angle.

@article{Marshall2013RandomizedTU,
  title={Randomized trial using ultrasound to assess intramuscular vaccination at a 60° or 90° needle angle.},
  author={Helen Siobhan Marshall and Michelle Frances Clarke and Susan Evans and Lino Piotto and Roger J. Gent},
  journal={Vaccine},
  year={2013},
  volume={31 23},
  pages={2647-52}
}
OBJECTIVE Globally, recommendations differ on the ideal angle of needle insertion to ensure vaccinate deposition in muscle for optimal safety and immunogenicity. This study aimed to compare the level of vaccinate deposition during vaccination, using two different needle angles (60° and 90°), in young children, adolescents and adults. METHODS In this randomized cross-over study, two doses of a licensed hepatitis vaccine, were administered to study participants, at a 60° or 90° angle using a… CONTINUE READING