• DOI:10.1093/EURHEARTJ/EHI115
Corpus ID: 15805662

Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS).

@article{Flather2005RandomizedTT,
  title={Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS).},
  author={M. Flather and M. Shibata and A. Coats and D. V. van Veldhuisen and A. Parkhomenko and J. Borbola and A. Cohen‐Solal and D. Dumitrascu and R. Ferrari and P. Lechat and J. Soler‐Soler and L. Tavazzi and L. {\vS}pinarov{\'a} and J. Toman and M. B{\"o}hm and S. Anker and S. Thompson and P. Poole‐Wilson},
  journal={European heart journal},
  year={2005},
  volume={26 3},
  pages={
          215-25
        }
}

• M. Flather, M. Shibata, +15 authors P. Poole‐Wilson
• Published 2005
• Medicine
• European heart journal

AIMS Large randomized trials have shown that beta-blockers reduce mortality and hospital admissions in patients with heart failure. [...] Key MethodMETHODS AND RESULTS We randomly assigned 2128 patients aged >/=70 years with a history of heart failure (hospital admission for heart failure within the previous year or known ejection fraction </=35%), 1067 to nebivolol (titrated from 1.25 mg once daily to 10 mg once daily), and 1061 to placebo.Expand

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