Randomized trial of the effect of zinc supplementation on the mental health of school-age children in Guatemala.

@article{DiGirolamo2010RandomizedTO,
  title={Randomized trial of the effect of zinc supplementation on the mental health of school-age children in Guatemala.},
  author={Ann M DiGirolamo and Manuel Ramirez-Zea and Meng Wang and Rafael C. Flores-Ayala and Reynaldo Martorell and Lynnette M Neufeld and Usha Ramakrishnan and Daniel W Sellen and M M Black and Aryeh D Stein},
  journal={The American journal of clinical nutrition},
  year={2010},
  volume={92 5},
  pages={1241-50}
}
BACKGROUND Rates of mental illness in children are increasing throughout the world. Observational studies of depression, anxiety, and attention-deficit hyperactivity disorder suggest that zinc is an alternative treatment. OBJECTIVE We examined the effect of zinc supplementation on the mental health of school-age children in Guatemala. DESIGN From January to October 2006, we conducted a 6-mo randomized, double-blind, controlled trial comparing zinc supplementation (10 mg ZnO/d for 5 d/wk… CONTINUE READING

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