Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases.

@article{Hartsell2005RandomizedTO,
  title={Randomized trial of short- versus long-course radiotherapy for palliation of painful bone metastases.},
  author={William F. Hartsell and Charles B. Scott and Deborah W. Bruner and Charles W. Scarantino and Robert Ivker and Mack Iii Roach and John H. Suh and William F. Demas and Benjamin Movsas and Ivy A. Petersen and Andre A. Konski and Charles S. Cleeland and Nora A. Janjan and Michelle L Desilvio},
  journal={Journal of the National Cancer Institute},
  year={2005},
  volume={97 11},
  pages={
          798-804
        }
}
BACKGROUND Radiation therapy is effective in palliating pain from bone metastases. We investigated whether 8 Gy delivered in a single treatment fraction provides pain and narcotic relief that is equivalent to that of the standard treatment course of 30 Gy delivered in 10 treatment fractions over 2 weeks. METHODS A prospective, phase III randomized study of palliative radiation therapy was conducted for patients with breast or prostate cancer who had one to three sites of painful bone… CONTINUE READING

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