Randomized trial of mediastinal lymph node sampling versus complete lymphadenectomy during pulmonary resection in the patient with N0 or N1 (less than hilar) non-small cell carcinoma: results of the American College of Surgery Oncology Group Z0030 Trial.

@article{Darling2011RandomizedTO,
  title={Randomized trial of mediastinal lymph node sampling versus complete lymphadenectomy during pulmonary resection in the patient with N0 or N1 (less than hilar) non-small cell carcinoma: results of the American College of Surgery Oncology Group Z0030 Trial.},
  author={Gail Elizabeth Darling and Mark S. Allen and P. Anthony Decker and Karla V. Ballman and Richard A. Malthaner and Richard I. Inculet and David R. Jones and Robert James McKenna and Rodney J. Landreneau and Valerie Rusch and Joe Bill Putnam},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2011},
  volume={141 3},
  pages={
          662-70
        }
}
OBJECTIVE To determine whether mediastinal lymph node dissection improves survival compared with mediastinal lymph node sampling in patients undergoing resection for N0 or nonhilar N1, T1, or T2 non-small cell lung cancer. METHODS Patients with non-small cell lung cancer underwent sampling of 2R, 4R, 7, and 10R for right-sided tumors and 5, 6, 7, and 10L for left-sided tumors. If all tumors were negative for malignancy, patients were randomized to no further lymph node sampling (mediastinal… CONTINUE READING
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