Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan.

@article{Ogawa2007RandomizedTO,
  title={Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan.},
  author={Akira Ogawa and Etsuro Mori and Kazuo Minematsu and Waro Taki and A. S. C. Takahashi and Shigeru Nemoto and Susumu Miyamoto and Makoto Sasaki and Takashi Inoue},
  journal={Stroke},
  year={2007},
  volume={38 10},
  pages={2633-9}
}
BACKGROUND AND PURPOSE The Middle Cerebral Artery Embolism Local Fibrinolytic Intervention Trial (MELT) Japan was organized to determine the safety and clinical efficacy of intraarterial infusion of urokinase (UK) in patients with stroke within 6 hours of onset. METHODS Patients with ischemic stroke presenting within 6 hours of onset and displaying occlusions of the M1 or M2 portion of the middle cerebral artery on carotid angiography were randomized to the UK or control groups. Clinical… CONTINUE READING

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