Randomized trial of inhaled beclomethasone dipropionate versus theophylline for moderate asthma during pregnancy.

  title={Randomized trial of inhaled beclomethasone dipropionate versus theophylline for moderate asthma during pregnancy.},
  author={Mitchell P. Dombrowski and Michael Schatz and Robert Wise and Elizabeth A. Thom and M. Landon and William C Mabie and Roger B. Newman and Donald McNellis and John C. Hauth and Marshall D. Lindheimer and Steve N. Caritis and Kenneth J. Leveno and Paul Meis and Menachem Miodovnik and Ronald J. Wapner and Michael W. Varner and Michael O'Sullivan and Deborah L. Conway},
  journal={American journal of obstetrics and gynecology},
  volume={190 3},
OBJECTIVE This study was undertaken to compare the efficacy of inhaled beclomethasone dipropionate to oral theophylline for the prevention of asthma exacerbation(s) requiring medical intervention. STUDY DESIGN A prospective, double-blind, double placebo-controlled randomized clinical trial of pregnant women with moderate asthma was performed. RESULTS There was no significant difference (P=.554) in the proportion of asthma exacerbations among the 194 women in the beclomethasone cohort (18.0… CONTINUE READING


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