Randomized trial of high-dose chemotherapy and hematopoietic progenitor-cell support in operable breast cancer with extensive lymph node involvement: final analysis with 7 years of follow-up.

@article{Schrama2002RandomizedTO,
  title={Randomized trial of high-dose chemotherapy and hematopoietic progenitor-cell support in operable breast cancer with extensive lymph node involvement: final analysis with 7 years of follow-up.},
  author={Jolanda G Schrama and Ian F. Faneyte and Jan H. Schornagel and Joke W. Baars and Johannes Leo Peterse and Marc Joan Van de Vijver and Otilia B Dalesio and Harm van Tinteren and Emiel J. Th. Rutgers and D J Richelt and Sjoerd Rodenhuis},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2002},
  volume={13 5},
  pages={689-98}
}
BACKGROUND The aim of this study was to present an update of overall (OS) and disease-free survival (DFS) and to evaluate the correlation between outcome and pathological findings at surgery in a randomized trial of high-dose chemotherapy following neoadjuvant chemotherapy and surgery in high-risk breast cancer patients. PATIENTS AND METHODS Ninety-seven women <60 years of age with breast cancer and extensive axillary lymph node involvement received three courses of FE120C (5-fluorouracil 500… CONTINUE READING
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