Randomized trial of dobutamine versus dopamine in preterm infants with low systemic blood flow.

@article{Osborn2002RandomizedTO,
  title={Randomized trial of dobutamine versus dopamine in preterm infants with low systemic blood flow.},
  author={David Andrew Osborn and Nick J Evans and Martin R. Kluckow},
  journal={The Journal of pediatrics},
  year={2002},
  volume={140 2},
  pages={183-91}
}
OBJECTIVE Our purpose was to determine if dobutamine or dopamine results in greater improvements in systemic blood flow in very preterm infants with low flow during the first 24 hours of life. STUDY DESIGN A 2-center, randomized, double-blind study. Infants (n = 42) with low superior vena cava (SVC) flow (<41 mL/kg/min) in the first 12 hours were randomly assigned to receive 10 mL/kg normal saline solution, followed by 10 microg/kg/minute of dobutamine or dopamine. If low flow persisted or… CONTINUE READING

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