Randomized trial of chemoendocrine therapy started before or after surgery for treatment of primary breast cancer.

@article{Powles1995RandomizedTO,
  title={Randomized trial of chemoendocrine therapy started before or after surgery for treatment of primary breast cancer.},
  author={Trevor J. Powles and Tom F Hickish and Andreas Makris and Sue E Ashley and Mary R O'Brien and V. A. Tidy and Susan E. Casey and Anthony G. Nash and Natalie Sacks and David Cosgrove},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1995},
  volume={13 3},
  pages={547-52}
}
PURPOSE To evaluate in a randomized clinical trial systemic chemoendocrine therapy used as primary (neo-adjuvant) treatment before surgery in women with primary operable breast cancer. PATIENTS AND METHODS Patients aged less than 70 years with clinically palpable, primary operable breast cancer diagnostically confirmed by fine-needle aspiration cytology (FNAC) and suitable for treatment with surgery, radiotherapy, cytotoxic chemotherapy, and tamoxifen were considered eligible. Patients… CONTINUE READING
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