Randomized trial of adjuvant therapy in colon carcinoma: 10-year results of NSABP protocol C-01.

@article{Smith2004RandomizedTO,
  title={Randomized trial of adjuvant therapy in colon carcinoma: 10-year results of NSABP protocol C-01.},
  author={Roy E. Smith and Linda H. Colangelo and H Samuel Wieand and Mirsada Begovic and Norman Wolmark},
  journal={Journal of the National Cancer Institute},
  year={2004},
  volume={96 15},
  pages={1128-32}
}
BACKGROUND The National Surgical Adjuvant Breast and Bowel Project C-01 trial reported in 1988 that, for patients with adenocarcinoma of the colon, compared with surgery alone, 1) postoperative chemotherapy with 1-(2-chloroethyl)-3-(4-trans-methylcyclohexyl)-1-nitrosourea (i.e., MeCCNU or semustine), vincristine, and 5-fluorouracil was associated with… CONTINUE READING