Randomized trial comparing neo-adjuvant versus adjuvant chemotherapy in operable locally advanced breast cancer (T4b N0-2 M0).

@article{Deo2003RandomizedTC,
  title={Randomized trial comparing neo-adjuvant versus adjuvant chemotherapy in operable locally advanced breast cancer (T4b N0-2 M0).},
  author={Suryanarayana V. S. Deo and Manisha Bhutani and Nootan Kumar Shukla and Vinod Raina and Goura Kishor Rath and Joydeep Purkayasth},
  journal={Journal of surgical oncology},
  year={2003},
  volume={84 4},
  pages={192-7}
}
BACKGROUND AND OBJECTIVES Locally advanced breast cancer (LABC) remains a major problem in developing countries. While trials utilizing neo-adjuvant chemotherapy demonstrate superior survival rates compared to historic controls, randomized studies evaluating the precise role of neo-adjuvant chemotherapy in LABC are lacking. In the present trial, neo-adjuvant chemotherapy was compared against adjuvant chemotherapy to assess survival advantage in operable T4b N0-2 M0 breast cancer. METHODS A… CONTINUE READING