Randomized trial comparing albumin and saline in the prevention of paracentesis-induced circulatory dysfunction in cirrhotic patients with ascites.

@article{Solavera2003RandomizedTC,
  title={Randomized trial comparing albumin and saline in the prevention of paracentesis-induced circulatory dysfunction in cirrhotic patients with ascites.},
  author={Javier Sola-vera and Josep Mi{\~n}ana and Elena Ricart and Montserrat Planella and Bego{\~n}a Gonz{\'a}lez and Xavier Torras and Jos{\'e} Simental Rodr{\'i}guez and Jos{\'e} Such and S Gal{\'a}n Pascual and Germ{\'a}n Soriano and Miguel P{\'e}rez-Mateo and Carlos Guarner},
  journal={Hepatology},
  year={2003},
  volume={37 5},
  pages={1147-53}
}
Paracentesis-induced circulatory dysfunction (PICD) is a recently described complication that can be prevented with the administration of plasma expanders. The aim of this study was to compare the efficacy of saline versus albumin in the prevention of PICD. Patients were randomized to receive albumin or saline after total paracentesis. Patients readmitted as a consequence of a second episode of tense ascites were treated with total paracentesis and the alternative plasma expander. After… CONTINUE READING