Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer.

@article{Ang2001RandomizedTA,
  title={Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer.},
  author={K. Kian Ang and Andy M. Trotti and Barry W. Brown and Adam Seth Garden and Robert L. Foote and William H. Morrison and Fady B Geara and Douglas W Klotch and Helmuth Goepfert and L. J. Peters},
  journal={International journal of radiation oncology, biology, physics},
  year={2001},
  volume={51 3},
  pages={571-8}
}
PURPOSE A multi-institutional, prospective, randomized trial was undertaken in patients with advanced head-and-neck squamous cell carcinoma to address (1) the validity of using pathologic risk features, established from a previous study, to determine the need for, and dose of, postoperative radiotherapy (PORT); (2) the impact of accelerating PORT using a concomitant boost schedule; and (3) the importance of the overall combined treatment duration on the treatment outcome. METHODS AND… CONTINUE READING
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