Randomized radiostereometric study comparing osteogenic protein-1 (BMP-7) and autograft bone in human noninstrumented posterolateral lumbar fusion: 2002 Volvo Award in clinical studies.

@article{Johnsson2002RandomizedRS,
  title={Randomized radiostereometric study comparing osteogenic protein-1 (BMP-7) and autograft bone in human noninstrumented posterolateral lumbar fusion: 2002 Volvo Award in clinical studies.},
  author={R. Johnsson and Bj{\"o}rn H Str{\"o}mqvist and Per Aspenberg},
  journal={Spine},
  year={2002},
  volume={27 23},
  pages={2654-61}
}
STUDY DESIGN Randomized efficacy trial comparing two types of noninstrumented posterolateral fusion between L5 and S1 in patients with L5 spondylolysis and vertebral slip less than 50%, as evaluated by radiostereometric analysis. OBJECTIVE To determine whether osteogenic protein-1 (BMP-7) in the OP-1 Implant yields better stabilizing bony fusion than autograft bone. SUMMARY OF BACKGROUND DATA Animal studies of osteoinductive proteins in noninstrumented posterolateral fusions have shown high… CONTINUE READING

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