Randomized prospective trial of the effect of induced hypergastrinemia on the prevention of pancreatic atrophy after pancreatoduodenectomy in humans.

@article{Jang2003RandomizedPT,
  title={Randomized prospective trial of the effect of induced hypergastrinemia on the prevention of pancreatic atrophy after pancreatoduodenectomy in humans.},
  author={Jin-Young Jang and S W Kim and J. S. Han and Sang-Jae Park and Youn-Chan Park and Young Joon Ahn and Yong-Hyun Park},
  journal={Annals of surgery},
  year={2003},
  volume={237 4},
  pages={522-9}
}
OBJECTIVE To investigate whether gastrin has regenerative effect on the pancreas and in particular whether it prevents the atrophy of the distal pancreas after resection of pancreas in humans. SUMMARY BACKGROUND DATA Although pancreatic regeneration after resection is well documented in animals, atrophy rather than regeneration of the distal remnant pancreas commonly occurs following pancreatoduodenectomy in humans. Of the many factors involving pancreatic regeneration, gastrin has been shown… CONTINUE READING