Randomized phase II study of paclitaxel and carboplatin or vinorelbine in advanced non-small cell lung cancer.

Abstract

BACKGROUND A randomized phase II trial was conducted to determine if two non-platinum protocols are able to yield a similar efficacy and toxicity profile as compared to two platinum-based doublets in advanced non-small cell lung cancer (NSCLC). PATIENTS AND METHODS A total of 61 patients were randomly assigned to a reference regimen of carboplatin and… (More)

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