Randomized double-blind comparison of serotonergic (Citalopram) versus noradrenergic (Reboxetine) reuptake inhibitors in outpatients with somatoform, DSM-IV-TR pain disorder.

@article{Aragona2005RandomizedDC,
  title={Randomized double-blind comparison of serotonergic (Citalopram) versus noradrenergic (Reboxetine) reuptake inhibitors in outpatients with somatoform, DSM-IV-TR pain disorder.},
  author={Massimiliano Aragona and Lara Bancheri and Donatella Perinelli and Lorenzo Tarsitani and Alessia Pizzimenti and Antonella Conte and Maurizio Inghilleri},
  journal={European journal of pain},
  year={2005},
  volume={9 1},
  pages={33-8}
}
OBJECTIVES Whether the effect of tricyclic antidepressants on Pain Disorder arises from their noradrenergic or serotonergic actions or both remains unclear. We compared the selective serotonin reuptake inhibitor (SSRI) citalopram and the noradrenergic reuptake inhibitor (NARI) reboxetine in outpatients with Pain Disorder. We also distinguished the drugs' analgesic and antidepressant effects. METHODS In this 8-week, randomized double-blind study, 35 patients with a DSM-IV-TR diagnosis of Pain… CONTINUE READING