Randomized controlled trials.

@article{Stolberg2004RandomizedCT,
  title={Randomized controlled trials.},
  author={Harald O. Stolberg and Geoffrey R Norman and Isabelle Trop},
  journal={AJR. American journal of roentgenology},
  year={2004},
  volume={183 6},
  pages={
          1539-44
        }
}
receding articles in this series have provided a great deal of information concerning research design and methodology, including research protocols, statistical analyses, and assessment of the clinical importance of radiologic research studies. Many methods of research design have already been presented, including descriptive studies (e.g., case reports, case series, and cross-sectional surveys), and some analytical designs (e.g., cohort and case-control studies). Case-control and cohort… 

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How well is the clinical importance of study results reported? An assessment of randomized controlled trials.

Authors of RCTs published in major general medical and internal medicine journals do not consistently provide their own interpretation of the clinical importance of their results, and they often do not provide sufficient information to allow readers to make their own interpretations.

Statistical power, sample size, and their reporting in randomized controlled trials.

The pattern over time in the level of statistical power and the reporting of sample size calculations in published randomized controlled trials (RCTs) with negative results is described and few trials discussed whether the observed differences were clinically important.

Better reporting of randomised controlled trials: the CONSORT statement

It is entirely reasonable to require higher standards for papers reporting randomised trials than those describing other types of study, since randomised controlled trials are the best way to compare the effectiveness of different interventions.

The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials

The revised CONSORT statement is intended to improve the reporting of an RCT, enabling readers to understand a trial's conduct and to assess the validity of its results.

Quality of reporting of randomized trials as a measure of methodologic quality.

Similar quality of reporting may hide important differences in methodologic quality, and well-conducted trials may be reported badly, so a clear distinction should be made between these 2 dimensions of the quality of RCTs.

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