Randomized controlled trial of adjuvant oral dexamethasone pulse therapy in pemphigus vulgaris: PEMPULS trial.

@article{Mentink2006RandomizedCT,
  title={Randomized controlled trial of adjuvant oral dexamethasone pulse therapy in pemphigus vulgaris: PEMPULS trial.},
  author={L. Mentink and Maria W. Mackenzie and G. T{\'o}th and M. Laseur and Frank P G Lambert and N. Veeger and G. Cianchini and M. Pavlovi{\'c} and M. Jonkman},
  journal={Archives of dermatology},
  year={2006},
  volume={142 5},
  pages={
          570-6
        }
}
OBJECTIVE To determine the therapeutic effect of adjuvant dexamethasone pulse therapy when given in addition to conventional treatment of pemphigus vulgaris. DESIGN A randomized, placebo-controlled trial. SETTING International European, multicenter outpatient and inpatient study. PATIENTS Of the 20 enrolled patients, 11 were randomized to the dexamethasone pulse (DP) group and 9 to the placebo pulse (PP) group. INTERVENTIONS Oral dexamethasone in 300-mg pulses or PPs 3 days per month… Expand
69 Citations

Paper Mentions

Interventional Clinical Trial
By this study, the investigators want to test if the value of adjuvant pulse glucocorticoid therapy for pemphigus can be determined by comparing an experimental arm (dexamethasone pulse… Expand
ConditionsPemphigus
InterventionDrug
Randomized controlled open-label trial of four treatment regimens for pemphigus vulgaris.
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