Randomized controlled trial comparing oral amoxicillin-clavulanate and ofloxacin with intravenous ceftriaxone and amikacin as outpatient therapy in pediatric low-risk febrile neutropenia.

@article{Gupta2009RandomizedCT,
  title={Randomized controlled trial comparing oral amoxicillin-clavulanate and ofloxacin with intravenous ceftriaxone and amikacin as outpatient therapy in pediatric low-risk febrile neutropenia.},
  author={Ajay Gupta and Chetanya Swaroop and Sandeep Agarwala and Ravindra Mohan Pandey and Sameer Bakhshi},
  journal={Journal of pediatric hematology/oncology},
  year={2009},
  volume={31 9},
  pages={
          635-41
        }
}
BACKGROUND Outpatient oral therapy is infrequently used in pediatric low-risk febrile neutropenia (LRFN) as there is insufficient data regarding its equivalence as compared with parenteral therapy. METHODS This is a single institutional, randomized control trial in pediatric LRFN aged 2 to 15 years, in which 123 episodes in 88 patients were randomized to outpatient oral ofloxacin 7.5 mg/kg 12 hourly and amoxycillin-clavulanate 12.5 mg/kg 8 hourly or outpatient intravenous (IV) ceftriaxone 75… CONTINUE READING
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