Randomized controlled trial comparing cerebral perfusion pressure-targeted therapy versus intracranial pressure-targeted therapy for raised intracranial pressure due to acute CNS infections in children.

@article{Kumar2014RandomizedCT,
  title={Randomized controlled trial comparing cerebral perfusion pressure-targeted therapy versus intracranial pressure-targeted therapy for raised intracranial pressure due to acute CNS infections in children.},
  author={Renuka Kumar and Sunit Singhi and Pratibha D. Singhi and Muralidharan Jayashree and Arun Bansal and Anuj Bhatti},
  journal={Critical care medicine},
  year={2014},
  volume={42 8},
  pages={1775-87}
}
OBJECTIVE In children with acute CNS infection, management of raised intracranial pressure improves mortality and neuromorbidity. We compared cerebral perfusion pressure-targeted approach with the conventional intracranial pressure-targeted approach to treat raised intracranial pressure in these children. DESIGN Prospective open-label randomized controlled trial. SETTING PICU in a tertiary care academic institute. PATIENTS Hundred ten children (1-12 yr) with acute CNS infections having… CONTINUE READING
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