Randomized controlled trial (RCT) of vitamin D supplementation in pregnancy in a population with endemic vitamin D deficiency.

@article{Dawodu2013RandomizedCT,
  title={Randomized controlled trial (RCT) of vitamin D supplementation in pregnancy in a population with endemic vitamin D deficiency.},
  author={Adekunle Dawodu and Hussein F Saadi and Gharid N Bekdache and Yasin Javed and Mekibib Altaye and Bruce W. Hollis},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2013},
  volume={98 6},
  pages={
          2337-46
        }
}
BACKGROUND Vitamin D (vD) deficiency in pregnancy is a global health problem and the amount of vD supplementation to prevent vD deficiency is controversial. OBJECTIVE The objective of the study was to determine effectiveness and safety of prenatal 2000 IU and 4000 IU/d compared with 400 IU/d vD3 supplementation in a randomized controlled trial in population in which vD deficiency is endemic. DESIGN/METHODS Arab women were randomized at 12-16 weeks of gestation to 400, 2000, and 4000 IU/d… CONTINUE READING