Randomized comparison of the effects of ASA plus clopidogrel versus ASA alone on early platelet activation in acute coronary syndromes with elevated high-sensitivity C-reactive protein and soluble CD40 ligand levels.

@article{Vavuranakis2006RandomizedCO,
  title={Randomized comparison of the effects of ASA plus clopidogrel versus ASA alone on early platelet activation in acute coronary syndromes with elevated high-sensitivity C-reactive protein and soluble CD40 ligand levels.},
  author={Manolis Vavuranakis and George Latsios and Dimitris Aggelis and Irini Bosinakou and Ioannis Karambelas and Dimitris Tousoulis and Kostas Toutouzas and Christodoulos Stefanadis},
  journal={Clinical therapeutics},
  year={2006},
  volume={28 6},
  pages={860-71}
}
BACKGROUND High-sensitivity C-reactive protein (hsCRP) and soluble cluster of differentiation 40 ligand (sCD40L) have been established as effective markers of inflammation in predicting the risk for adverse outcomes in patients with acute coronary syndromes (ACSs). Activated platelets secrete certain inflammatory mediators such as P-selectin and sCD40L… CONTINUE READING