Randomized comparison of intravenous versus intracoronary streptokinase for myocardial infarction.

@article{Alderman1984RandomizedCO,
  title={Randomized comparison of intravenous versus intracoronary streptokinase for myocardial infarction.},
  author={Edwin L. Alderman and Kenneth R Jutzy and L E Berte and Redonda G Miller and Jonathan R. Friedman and W P Creger and Michael Eliastam},
  journal={The American journal of cardiology},
  year={1984},
  volume={54 1},
  pages={14-9}
}
The efficacy of intravenous (i.v.) thrombolytic therapy has not been firmly established in comparison with the intracoronary (i.c.) route of administration. In a randomized trial of 28 patients who underwent angiography before and during i.v. and i.c. administration of streptokinase (STK), recanalization was achieved in 73% of patients who received the drug by the i.c. route, compared with 62% of patients who received the drug by the i.v. route (difference not significant). Reopening took 28… CONTINUE READING

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