Randomized comparison of chloroquine and amodiaquine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.

@article{Sowunmi2001RandomizedCO,
  title={Randomized comparison of chloroquine and amodiaquine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.},
  author={A. Sowunmi and Adejumoke Idowu Ayede and Adegoke Gbadegesin Falade and V N Ndikum and C O Sowunmi and Ahmed Adebowale Adedeji and Catherine Olufunke Falade and T Christian Happi and Ayoade M. J. Oduola},
  journal={Annals of tropical medicine and parasitology},
  year={2001},
  volume={95 6},
  pages={549-58}
}
The increasing resistance of Plasmodium falciparum to chloroquine (CQ) has created an urgent need for the evaluation of alternative, effective, safe, cheap, readily available and affordable antimalarial treatments. In the present study, the efficacy of amodiaquine (AQ) in the treatment of acute, symptomatic, uncomplicated, P. falciparum malaria was compared with that of CQ, each drug being given at 10 mg/kg per day for 3 days (days 0, 1 and 2). The 210 subjects (104 given AQ and 106 CQ) were… CONTINUE READING

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