Randomized comparative multicenter study of hydroxyethyl starch versus albumin as a plasma expander in cirrhotic patients with tense ascites treated with paracentesis.

@article{Altman1998RandomizedCM,
  title={Randomized comparative multicenter study of hydroxyethyl starch versus albumin as a plasma expander in cirrhotic patients with tense ascites treated with paracentesis.},
  author={Claude Altman and Brigitte Bernard and Dominique Roulot and R L Vitte and Olivier Ink},
  journal={European journal of gastroenterology & hepatology},
  year={1998},
  volume={10 1},
  pages={5-10}
}
OBJECTIVE Large-volume paracentesis associated with plasma volume expansion with albumin is an effective, safe, but costly therapy for ascites in patients with cirrhosis. The aim of this study was to compare the use of a synthetic plasma expander, hydroxyethyl starch (HES), with that of albumin. DESIGN Sixty cirrhotic patients with ascites were studied. Patients were randomly assigned to be infused with either albumin (8 g/l of ascites removed, n = 33) or HES (200 ml/l of ascites removed, n… CONTINUE READING