Randomized clinical trial of adjuvant mitomycin plus tegafur in patients with resected stage III gastric cancer.

@article{Cirera1999RandomizedCT,
  title={Randomized clinical trial of adjuvant mitomycin plus tegafur in patients with resected stage III gastric cancer.},
  author={Llu{\'i}s Padr{\'o} Cirera and Ana Balil and Eduard Batiste-Alentorn and Ignacio Tusquets and Teresa Cardona and {\`A}ngels Arcusa and L. Jolis and Eugeni Saig{\'i} and Immaculada Guasch and Alain Badia and Montserrat Boleda},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1999},
  volume={17 12},
  pages={3810-5}
}
PURPOSE The efficacy of adjuvant chemotherapy in gastric cancer is controversial. We conducted a phase III, randomized, multicentric clinical trial with the goal of assessing the efficacy of the combination of mitomycin plus tegafur in prolonging the disease-free survival and overall survival of patients with resected stage III gastric cancer. PATIENTS AND METHODS Patients with resected stage III gastric adenocarcinoma were randomly assigned, using sealed envelopes, to receive either… CONTINUE READING

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