Randomized Tria l o f Cytoreduct ion and Hyperthermic Intraper i toneal Chemotherapy Versus Systemic Chemotherapy and Pal l ia t i ve Surgery in Pat ients With Per i toneal Carc inomatos is of Colorecta l Cancer

@inproceedings{Verwaal2003RandomizedTL,
  title={Randomized Tria l o f Cytoreduct ion and Hyperthermic Intraper i toneal Chemotherapy Versus Systemic Chemotherapy and Pal l ia t i ve Surgery in Pat ients With Per i toneal Carc inomatos is of Colorecta l Cancer},
  author={Vic J. Verwaal and Serge van Ruth and Eelco de Bree and Gooike W. van Slooten and Harm van Tinteren and Henk Boot and Frans A N Zoetmulder},
  year={2003}
}
Purpose: To confirm the findings from uncontrolled studies that aggressive cytoreduction in combination with hyperthermic intraperitoneal chemotherapy (HIPEC) is superior to standard treatment in patients with peritoneal carcinomatosis of colorectal cancer origin. Patients and Methods: Between February 1998 and August 2001, 105 patients were randomly assigned to receive either standard treatment consisting of systemic chemotherapy (fluorouracil-leucovorin) with or without palliative surgery, or… CONTINUE READING

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